Description

n-(4-(7-(Diethylamino)-4-Methylcoumarin-3-Yl))Maleimide CAS NO 93111-28-5 is a highly functionalized, fluorescent maleimide derivative, belonging to the coumarin dye family. This compound is critical for researchers and manufacturers requiring a reactive, fluorescent probe for site-specific labeling of thiol groups in proteins, peptides, and other biomolecules. It is primarily utilized in advanced life science research, diagnostics development, and the synthesis of functional materials where precise optical tracking is essential.

Application

• Bioconjugation & Protein Labeling: Acts as a key reagent for covalent attachment of a fluorescent coumarin tag to cysteine residues in proteins and antibodies for fluorescence microscopy, flow cytometry, and immunoassays.
• Biomolecular Probes & Sensors: Used in the development of fluorescent probes and biosensors to study protein dynamics, interactions, and localization in live or fixed cells.
• Polymer & Material Science: Serves as a functional monomer or cross-linker in the synthesis of smart polymers, hydrogels, and coatings with intrinsic fluorescence for property analysis.
• Diagnostic Kit Development: Employed in the manufacturing of fluorescent detection components for diagnostic kits and lateral flow assays.
• Chemical Biology Research: A valuable tool for chemists and biologists studying enzyme activity, protein folding, and other biochemical pathways through fluorescence-based techniques.

Basic Information

Product Name	n-(4-(7-(Diethylamino)-4-Methylcoumarin-3-Yl))Maleimide
CAS No.	93111-28-5
Molecular Formula	C19H20N2O4
Molecular Weight	340.38 g/mol
Synonyms	7-(Diethylamino)-4-methyl-3-[(maleimido)methyl]coumarin; 3-Maleimidomethyl-7-diethylaminocoumarin; MDCC maleimide; CPM maleimide derivative; N-[4-(7-Diethylamino-4-methyl-2-oxo-2H-chromen-3-yl)phenyl]maleimide; Fluorescent maleimide coumarin dye; Thiol-reactive coumarin dye
EINECS	Contact for details

Quality Control

Our production of n-(4-(7-(Diethylamino)-4-Methylcoumarin-3-Yl))Maleimide adheres to stringent in-house quality protocols to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Fluorescence Properties	Ex/Em ~430/470 nm (solvent dependent)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.