Description

2-n-(3-Aminopropyl)-Amino-5-Bromopyridine CAS NO 92993-40-3 is a specialized brominated pyridine derivative featuring both an aminopropyl side chain and a primary amine, making it a versatile bifunctional building block for advanced synthesis. This compound is particularly valuable for its role in constructing complex molecular architectures, especially in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and life science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides, leveraging its halogen and amine functionalities for bioactivity.
• Ligand and Catalyst Development: Serves as a chelating agent or precursor for metal-organic frameworks (MOFs) and homogeneous catalysis due to its nitrogen-rich structure.
• Material Science Research: Employed in the creation of functional polymers, dyes, and organic electronic materials where its bromine group allows for further cross-coupling reactions.
• Bioconjugation and Probe Synthesis: The primary amine group is ideal for coupling with carboxylic acids or activated esters to create fluorescent probes, biomarkers, or antibody-drug conjugates (ADCs).
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the global pharmaceutical and biotechnology sectors.

Basic Information

Product Name	2-n-(3-Aminopropyl)-Amino-5-Bromopyridine
CAS No.	92993-40-3
Molecular Formula	C8H12BrN3
Molecular Weight	230.11 g/mol
Synonyms	5-Bromo-2-[(3-aminopropyl)amino]pyridine; 2-[(3-Aminopropyl)amino]-5-bromopyridine; N1-(5-Bromopyridin-2-yl)propane-1,3-diamine; 5-Bromo-N2-(3-aminopropyl)pyridine-2-amine; 92993-40-3; 2-Amino-5-bromo-N-(3-aminopropyl)pyridine
EINECS	Contact for details

Quality Control

Our 2-n-(3-Aminopropyl)-Amino-5-Bromopyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.