Description

2-(2-Aminoethylamino)-5-Chloropyridine is a versatile bifunctional organic intermediate featuring both a primary amine and a chloropyridine moiety. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides, leveraging its reactive sites for structural diversification.
• Ligand and Chelating Agent Precursor: Serves as a starting material for synthesizing polydentate ligands used in catalysis and metal complexation.
• Polymer and Material Science: Employed in the creation of functionalized polymers, dyes, and advanced organic materials.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Cross-coupling Reactions: The chloro substituent makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).

Basic Information

Product Name	2-(2-Aminoethylamino)-5-Chloropyridine
CAS No.	92992-92-2
Molecular Formula	C7H10ClN3
Molecular Weight	171.63 g/mol
Synonyms	5-Chloro-2-[(2-aminoethyl)amino]pyridine; N1-(5-Chloropyridin-2-yl)ethane-1,2-diamine; 2-(2-Aminoethylamino)-5-chloropyridine; 1-(5-Chloro-2-pyridinyl)-2-ethylenediamine; 5-Chloro-N-(2-aminoethyl)pyridin-2-amine; 2-Aminoethyl-(5-chloro-2-pyridyl)amine; 92992-92-2
EINECS	Contact for details

Quality Control

Our 2-(2-Aminoethylamino)-5-Chloropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.