Description

6-Chloro-1,2-Dihydro-2-Oxospiro[4H-3,1-Benzoxazin-4,4'-Piperidine] is a high-purity, advanced pharmaceutical intermediate with a complex spirocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, especially for neurological and psychiatric disorders.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry & Scale-Up: Serves as a critical raw material for process research, route scouting, and pilot-scale API synthesis.
• Reference Standard: Employed as an analytical standard for method development, validation, and quality control in API manufacturing.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and spiro compound reactivity.
• Custom Synthesis: A starting point for the custom synthesis of more complex, proprietary molecules for client-specific projects.

Basic Information

Product Name	6-Chloro-1,2-Dihydro-2-Oxospiro[4H-3,1-Benzoxazin-4,4'-Piperidine]
CAS No.	92926-63-1
Molecular Formula	C12H11ClN2O2
Molecular Weight	250.68 g/mol
Synonyms	6-Chloro-2H-spiro[1,3-benzoxazine-4,4'-piperidine]-2-one; 6-Chloro-1,2-dihydro-2-oxospiro[4H-3,1-benzoxazine-4,4'-piperidine]; 6-Chloro-2-oxo-1,2-dihydrospiro[3,1-benzoxazine-4,4'-piperidine]; 92926-63-1; Spiro[4H-3,1-benzoxazine-4,4'-piperidine], 6-chloro-1,2-dihydro-2-oxo-; 6-Chloro-2-oxospiro[benzoxazine-4,4'-piperidine]
EINECS	Contact for details

Quality Control

Our 6-Chloro-1,2-Dihydro-2-Oxospiro[4H-3,1-Benzoxazin-4,4'-Piperidine] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.