Description

6-Fluorospiro[4H-3,1-Benzoxazine-4,4'-Piperidin]-2(1H)-One CAS NO 92926-32-4 is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic benzoxazine-piperidine scaffold. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders. It is primarily sought after by research institutions, custom synthesis organizations, and pharmaceutical companies engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug molecules, especially those with neurological activity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• CNS Drug Development: Used in the research and development of new therapeutics for conditions such as anxiety, depression, and cognitive disorders.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and novel synthetic pathways.
• Process Chemistry Optimization: Employed in scaling up synthetic routes from laboratory to pilot plant scale.

Basic Information

Product Name	6-Fluorospiro[4H-3,1-Benzoxazine-4,4'-Piperidin]-2(1H)-One
CAS No.	92926-32-4
Molecular Formula	C12H13FN2O2
Molecular Weight	236.25 g/mol
Synonyms	6-Fluoro-1,2-dihydrospiro[4H-3,1-benzoxazine-4,4'-piperidin]-2-one; 6-Fluoro-2H-spiro[1,3-benzoxazine-4,4'-piperidine]-2-one; 6-Fluorospiro[benzoxazine-4,4'-piperidin]-2(1H)-one; 92926-32-4; Spiro[4H-3,1-benzoxazine-4,4'-piperidine]-2(1H)-one, 6-fluoro-
EINECS	Contact for details

Quality Control

Our 6-Fluorospiro[4H-3,1-Benzoxazine-4,4'-Piperidin]-2(1H)-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data, including HPLC, NMR, and MS, to verify identity and purity. Certificates of Analysis (COA) are available for every batch and supplied upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.