Description

6-Mercaptonicotinic Acid is a versatile sulfur-containing heterocyclic building block with a reactive thiol and carboxylic acid group. This dual functionality makes it a critical intermediate for synthesizing complex molecules in advanced research and industrial applications. It is primarily sought after by pharmaceutical, agrochemical, and material science industries for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used to construct active ingredients for crop protection products, leveraging its heterocyclic structure.
• Ligand and Chelating Agent: Serves as a building block for creating ligands used in catalysis and metal complexation studies.
• Material Science Research: Employed in the development of functional polymers and advanced organic materials due to its reactive sites.
• Bioconjugation Chemistry: The thiol group allows for site-specific modification of proteins and other biomolecules.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry and exploratory synthetic chemistry projects.

Basic Information

Product Name	6-Mercaptonicotinic Acid
CAS No.	92823-43-3
Molecular Formula	C6H5NO2S
Molecular Weight	155.17 g/mol
Synonyms	6-Sulfanylpyridine-3-carboxylic acid; 3-Carboxy-2-mercaptopyridine; 2-Mercaptonicotinic acid; 6-Thionicotinic acid; 2-Pyridinethiol-5-carboxylic acid; 5-Carboxy-2-pyridinethiol; 6-Mercapto-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Mercaptonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and residual solvent analysis, to ensure it meets high-purity standards suitable for research and industrial synthesis. Certificates of Analysis (COA) are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to minimize oxidation and degradation. Allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.