Description

(+/-) 3-Ethyl-3-(4-Pyridinyl)-2,6-Piperidinedione CAS NO 92788-10-8 is a high-purity, synthetic heterocyclic compound belonging to the piperidinedione class, serving as a critical advanced pharmaceutical intermediate (API intermediate). Its value lies in its unique molecular scaffold, which is essential for constructing complex bioactive molecules in medicinal chemistry research and development. This compound is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing novel therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities (NCEs).
• Preclinical Development: Serves as a critical raw material for producing compounds required for pharmacological and toxicological evaluation.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for scale-up synthesis under cGMP conditions for clinical trial material production.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Details
Product Name	(+/-) 3-Ethyl-3-(4-Pyridinyl)-2,6-Piperidinedione
CAS No.	92788-10-8
Molecular Formula	C12H14N2O2
Molecular Weight	218.25 g/mol
Synonyms	3-Ethyl-3-(4-pyridyl)piperidine-2,6-dione; 3-Ethyl-3-(pyridin-4-yl)piperidine-2,6-dione; 2,6-Piperidinedione, 3-ethyl-3-(4-pyridinyl)-; 3-(4-Pyridinyl)-3-ethyl-2,6-piperidinedione; 3-Ethyl-3-(4-pyridinyl)-2,6-piperidinedione; 3-Ethyl-3-(4-pyridyl)-2,6-dioxopiperidine; (±)-3-Ethyl-3-(4-pyridinyl)piperidine-2,6-dione
EINECS	Contact for details

Quality Control

Our (+/-) 3-Ethyl-3-(4-Pyridinyl)-2,6-Piperidinedione is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR, IR, and MS, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development projects with custom purity grades and analytical method support upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.