Description

4',3,4-Trihydroxychalcone is a polyphenolic flavonoid compound belonging to the chalcone subclass, known for its distinctive molecular structure and significant biological activity. This compound serves as a crucial intermediate and active research chemical in the development of novel pharmaceutical and nutraceutical agents. It is primarily sought by researchers and manufacturers in the pharmaceutical, cosmetic, and life science industries for its potential therapeutic properties.

Application

• Pharmaceutical Research & Development: As a key intermediate in synthesizing more complex flavonoids and as a lead compound for investigating anti-inflammatory, antioxidant, and anticancer activities.
• Nutraceutical Formulation: Potential inclusion in dietary supplements targeting oxidative stress, due to its polyphenolic antioxidant profile.
• Cosmeceutical Ingredients: Research into skincare formulations for its potential anti-aging and photoprotective effects against UV-induced skin damage.
• Biochemical Research: Used as a standard or probe in enzymatic studies, particularly those involving tyrosine kinase, COX-2, or other inflammatory pathway enzymes.
• Agrochemical Development: Exploration of natural product-based agents for plant protection and growth regulation.

Basic Information

Product Name	4',3,4-Trihydroxychalcone
CAS No.	92496-89-4
Molecular Formula	C15H12O4
Molecular Weight	256.25 g/mol
Synonyms	2-Propen-1-one, 1-(3,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-; (E)-1-(3,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one; 3,4,4'-Trihydroxychalcone; 3',4,4'-Trihydroxychalcone; 4,3',4'-Trihydroxychalcone; NSC 407303; Butein (Note: Butein is a common name for this compound)
EINECS	Contact for details

Quality Control

Every batch of 4',3,4-Trihydroxychalcone is produced and controlled under a strict quality management system. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) with detailed results from HPLC, NMR, and MS analyses to verify identity, purity, and potency. Our standard research grade typically meets a purity specification of ≥95% (HPLC), with higher purity grades available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.