Description

(E)-2-Methyl-2-Butenoic Acid (4R)-2,4,5,5A,6,7,8,9,9Aβ,9Bα-Decahydro-6α-Hydroxy-3-(Hydroxymethyl)-5Aα-Methyl-9-Methylene-2-Oxonaphtho[1,2-B]Furan-4α-Yl Ester is a high-purity, complex organic ester with a defined stereochemistry, serving as a critical advanced intermediate in sophisticated chemical synthesis. Its precise molecular architecture makes it an invaluable building block for research and development in the pharmaceutical and fine chemical sectors. This compound is essential for scientists and manufacturers requiring a reliable source of a structurally defined intermediate for creating novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral building block in the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly for complex therapeutic agents.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex natural product analogs and other high-value specialty organic molecules.
• Medicinal Chemistry Research: Serves as a precise scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the efficient production of target molecules in pilot and commercial-scale manufacturing.
• Biochemical Research: Potential use as a probe or precursor in studying specific enzymatic pathways or biological mechanisms due to its defined stereochemistry.

Basic Information

Product Name	(E)-2-Methyl-2-Butenoic Acid (4R)-2,4,5,5A,6,7,8,9,9Aβ,9Bα-Decahydro-6α-Hydroxy-3-(Hydroxymethyl)-5Aα-Methyl-9-Methylene-2-Oxonaphtho[1,2-B]Furan-4α-Yl Ester
CAS No.	92484-28-1
Molecular Formula	C₂₀H₂₈O₆
Molecular Weight	364.43 g/mol
Synonyms	2-Methylcrotonic Acid (4R)-2,4,5,5A,6,7,8,9,9Aβ,9Bα-Decahydro-6α-Hydroxy-3-(Hydroxymethyl)-5Aα-Methyl-9-Methylene-2-Oxonaphtho[1,2-B]Furan-4α-Yl Ester; Tiglic Acid (4R)-2,4,5,5A,6,7,8,9,9Aβ,9Bα-Decahydro-6α-Hydroxy-3-(Hydroxymethyl)-5Aα-Methyl-9-Methylene-2-Oxonaphtho[1,2-B]Furan-4α-Yl Ester; (E)-2-Methylbut-2-enoic Acid (4R)-2,4,5,5A,6,7,8,9,9Aβ,9Bα-Decahydro-6α-Hydroxy-3-(Hydroxymethyl)-5Aα-Methyl-9-Methylene-2-Oxonaphtho[1,2-B]Furan-4α-Yl Ester; 92484-28-1; A complex diterpenoid ester derivative
EINECS	Contact for details

Quality Control

Our (E)-2-Methyl-2-Butenoic Acid (4R)-2,4,5,5A,6,7,8,9,9Aβ,9Bα-Decahydro-6α-Hydroxy-3-(Hydroxymethyl)-5Aα-Methyl-9-Methylene-2-Oxonaphtho[1,2-B]Furan-4α-Yl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.