Description

4-Azidoretinol is a specialized, light-sensitive retinoid derivative that serves as a critical synthetic intermediate and research tool. This compound matters for its unique azide functional group, which enables bioorthogonal click chemistry reactions for labeling and probing biological systems. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in drug discovery, proteomics, and the development of novel therapeutic agents.

Application

• Bioconjugation & Click Chemistry: Acts as a key reagent for site-specific labeling of proteins, lipids, and other biomolecules via azide-alkyne cycloaddition.
• Retinoid Research: Used as a molecular probe to study retinoid metabolism, signaling pathways, and receptor interactions in cellular models.
• Pharmaceutical Intermediate: Serves as a versatile building block in the synthesis of novel retinoid-based drug candidates and targeted therapies.
• Proteomics & Imaging: Enables the tagging and visualization of retinoid-binding proteins in complex biological samples for advanced analytical studies.
• Chemical Biology Tool: Facilitates the development of activity-based probes to investigate enzyme function and metabolic pathways involving vitamin A derivatives.
• Material Science: Potential use in creating functionalized surfaces or polymers with bioactive retinoid properties for specialized applications.

Basic Information

Product Name	4-Azidoretinol
CAS No.	92484-22-5
Molecular Formula	C20H27N3O
Molecular Weight	325.45 g/mol
Synonyms	4-Azidoretinol; Retinyl Azide; 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-4-azido-2,4,6,8-nonatetraen-1-ol; 4-Azido-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol; Vitamin A Azide; All-trans-4-Azidoretinol
EINECS	Contact for details

Quality Control

Our 4-Azidoretinol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific data are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen). The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange solid or oil
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%
Solubility	Soluble in DMSO, DMF, and common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.