Description

Benzyl (S)-2-(((Benzyloxy)Carbonyl)Amino)-5-((tert-Butoxycarbonyl)Amino)Pentanoate is a high-purity, protected amino acid derivative essential for advanced peptide synthesis. This compound serves as a critical building block, enabling the precise construction of complex peptide sequences with controlled stereochemistry. It is primarily utilized by pharmaceutical R&D departments, biotechnology companies, and fine chemical manufacturers developing therapeutic peptides, peptidomimetics, and other bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential assembly of peptides on resin, particularly for introducing lysine or ornithine derivatives with orthogonal protecting groups.
• Solution-Phase Peptide Synthesis: Used in classical coupling strategies for constructing peptide fragments in solution, offering flexibility in complex molecule assembly.
• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) for peptide-based drugs targeting metabolic disorders, oncology, and infectious diseases.
• Bioconjugation and Labeling: The reactive carboxyl and amine functionalities (when deprotected) can be used to attach peptides to other molecules, such as fluorophores, polymers, or drug delivery carriers.
• Research & Development: Employed in academic and industrial labs for exploring novel peptide structures, studying structure-activity relationships (SAR), and developing new synthetic methodologies.
• Production of Custom Peptides: A vital raw material for CROs and CDMOs specializing in the contract manufacturing of non-GMP and GMP-grade peptides for clinical trials.

Basic Information

Item	Details
Product Name	Benzyl (S)-2-(((Benzyloxy)Carbonyl)Amino)-5-((tert-Butoxycarbonyl)Amino)Pentanoate
CAS No.	92455-57-7
Molecular Formula	C25H32N2O6
Molecular Weight	456.53 g/mol
Synonyms	Nα-Cbz-Nε-Boc-L-Lysine benzyl ester; (S)-Benzyl 2-((((benzyloxy)carbonyl)amino)-5-((tert-butoxycarbonyl)amino)pentanoate; Boc-Lys(Cbz)-OBzl; Nα-Z-Nε-Boc-L-Lysine-OBzl; Z-Lys(Boc)-OBzl; Benzyl Nα-carbobenzoxy-Nε-tert-butoxycarbonyl-L-lysinate; L-Lysine, N2-[N-(benzyloxy)carbonyl]-, N6-[(1,1-dimethylethoxy)carbonyl]-, benzyl ester
EINECS	Contact for details

Quality Control

Our Benzyl (S)-2-(((Benzyloxy)Carbonyl)Amino)-5-((tert-Butoxycarbonyl)Amino)Pentanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR and MS for structural confirmation, and residual solvent analysis. We provide detailed Certificates of Analysis (COA) to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.