Description

2,3,4-Tri-o-Acetyl-α-D-Glucuronide Methyl Ester Trichloroacetimidate is a high-purity, advanced synthetic intermediate crucial for the stereoselective construction of glycosidic bonds. This compound matters because it serves as a key glycosyl donor, enabling the efficient and controlled synthesis of complex oligosaccharides and glycoconjugates. It is primarily needed by research institutions and pharmaceutical companies engaged in carbohydrate chemistry, glycobiology research, and the development of novel therapeutics, vaccines, and diagnostic agents.

Application

• Glycosylation Reactions: Acts as a critical glycosyl donor in chemical and chemoenzymatic synthesis for the formation of α-linked glucuronide derivatives.
• Oligosaccharide Synthesis: Used in the stepwise assembly of complex oligosaccharides and polysaccharides for structural studies and bioactivity screening.
• Glycoconjugate Production: Essential for synthesizing glycoproteins, glycolipids, and other bioactive glycoconjugates with potential therapeutic applications.
• Pharmaceutical Intermediate: Serves as a key building block in the research and development of carbohydrate-based drugs, including anticoagulants and anti-inflammatory agents.
• Biochemical Probe Development: Utilized to create labeled or modified sugar moieties for studying carbohydrate-protein interactions and metabolic pathways.
• Standards and References: Provides a high-purity standard for analytical method development and quality control in carbohydrate analysis.

Basic Information

Item	Detail
Product Name	2,3,4-Tri-o-Acetyl-α-D-Glucuronide Methyl Ester Trichloroacetimidate
CAS No.	92420-89-8
Molecular Formula	C16H20Cl3NO10
Molecular Weight	492.69 g/mol
Synonyms	Methyl (2,3,4-tri-O-acetyl-α-D-glucopyranosyluronate) trichloroacetimidate; α-D-Glucopyranuronic acid, methyl ester, 2,3,4-triacetate, trichloroacetimidate; Trichloroacetimidic acid 2,3,4-tri-O-acetyl-α-D-glucopyranuronosyl methyl ester; Glucuronide trichloroacetimidate donor; Glycosyl trichloroacetimidate donor
EINECS	Contact for details

Quality Control

Our 2,3,4-Tri-o-Acetyl-α-D-Glucuronide Methyl Ester Trichloroacetimidate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.