Description

1-Benzothiophen-5-Yl Isocyanate is a specialized aromatic isocyanate building block, essential for the synthesis of complex heterocyclic compounds. Its core value lies in enabling the precise introduction of the isocyanate functional group onto the benzothiophene scaffold, a key step in creating novel molecular architectures. This high-purity intermediate is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics targeting various diseases.
• Agrochemical Research: Used in creating advanced pesticides and herbicides, where the benzothiophene core contributes to specific biological activity and environmental stability.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialized polymers, coatings, and resins with tailored thermal or mechanical properties.
• Chemical Synthesis: A versatile reagent for constructing urea and carbamate derivatives via reaction with amines and alcohols, expanding chemical libraries for screening.
• Dye and Pigment Industry: Employed in the synthesis of advanced organic dyes and functional pigments due to its fused aromatic structure.

Basic Information

Product Name	1-Benzothiophen-5-Yl Isocyanate
CAS No.	239097-78-0
Molecular Formula	C9H5NOS
Molecular Weight	175.21 g/mol
Synonyms	5-Isocyanatobenzothiophene; Benzo[b]thiophen-5-yl isocyanate; 1-Benzothiophene-5-isocyanate; 5-Benzothienyl isocyanate; Isocyanic acid, 1-benzothiophen-5-yl ester; 5-Isocyanato-1-benzothiophene; 239097-78-0; 5-Benzothiophenyl isocyanate
EINECS	Contact for details

Quality Control

Our 1-Benzothiophen-5-Yl Isocyanate is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting identity, assay, and impurity profiles to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, open flames, and incompatible materials such as alcohols, amines, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.