Description

1-tert-Butyl-3-Ethylcarbodiimide is a versatile and highly reactive carbodiimide coupling agent, essential for facilitating the formation of amide bonds under mild conditions. Its primary value lies in its role as a superior alternative to other carbodiimides, offering enhanced stability and selectivity in complex synthetic pathways, particularly in peptide synthesis and bioconjugation. This reagent is critically needed by research and development laboratories, pharmaceutical intermediates manufacturers, and fine chemical producers engaged in the synthesis of peptides, proteins, and other bioactive molecules.

Application

• Peptide Synthesis: As a key coupling agent for the formation of amide bonds between amino acids, minimizing racemization.
• Bioconjugation Chemistry: For linking biomolecules such as proteins, antibodies, or oligonucleotides to drugs, dyes, or solid supports.
• Pharmaceutical Intermediate Manufacturing: In the synthesis of active pharmaceutical ingredients (APIs) and complex organic molecules requiring amide bond formation.
• Polymer Chemistry: Used in the production of polyamides, polyurethanes, and other specialty polymers.
• Material Science: For surface functionalization and cross-linking applications to modify material properties.
• Agrochemical Synthesis: In the production of certain herbicides, fungicides, and plant growth regulators.

Basic Information

Product Name	1-tert-Butyl-3-Ethylcarbodiimide
CAS No.	1433-27-8
Molecular Formula	C9H18N2
Molecular Weight	154.25 g/mol
Synonyms	tert-Butylethylcarbodiimide; TBEC; Ethyl-tert-butylcarbodiimide; 1-(tert-Butyl)-3-ethylcarbodiimide; 1-Ethyl-3-tert-butylcarbodiimide; N-tert-Butyl-N'-ethylcarbodiimide; Carbodiimide, tert-butylethyl-; N-Ethyl-N'-tert-butylcarbodiimide
EINECS	215-857-6

Quality Control

Our 1-tert-Butyl-3-Ethylcarbodiimide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including assay by titration and impurity profiling, to meet the stringent requirements of research and industrial applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can degrade the product. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (Titration)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.