Description

4-Methoxybenzyl Isocyanide is a versatile organic building block characterized by its reactive isocyanide functional group. This compound is crucial for the synthesis of complex heterocycles and natural product analogs, enabling efficient multi-component reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for lead optimization and novel scaffold construction.

Application

• Pharmaceutical Intermediates: A key reagent in the Ugi and Passerini multi-component reactions for the rapid generation of diverse compound libraries for drug discovery.
• Agrochemical Synthesis: Used in the construction of novel pesticidal and herbicidal agents with complex molecular architectures.
• Material Science: Serves as a building block for functional polymers and advanced organic materials with tailored properties.
• Chemical Biology: Employed in the synthesis of activity-based probes and bioconjugates for studying biological processes.
• Catalyst Ligand Precursor: Utilized in the preparation of specialized ligands for transition metal catalysis.
• Academic & Industrial R&D: Fundamental reagent for methodological development in organic synthesis and novel reaction exploration.

Basic Information

Product Name	4-Methoxybenzyl Isocyanide
CAS No.	1197-58-6
Molecular Formula	C9H9NO
Molecular Weight	147.17 g/mol
Synonyms	p-Methoxybenzyl isocyanide; (4-Methoxyphenyl)methyl isocyanide; 1-Isocyano-1-(4-methoxyphenyl)methane; 4-Methoxybenzylisonitrile; Anisyl isocyanide; PMBI
EINECS	214-824-7

Quality Control

Our 4-Methoxybenzyl Isocyanide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity assessment and spectroscopic identification, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its highly volatile and light-sensitive nature, containers should be kept sealed and allowed to equilibrate to room temperature before opening to minimize moisture ingress and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.