Description

(Z)-2-(Hydroxymethyl)-2-Butenoic Acid (3Ar)-2,3,3Aβ,4,5,5A,6,7,9Aβ,9Bα-Decahydro-6α-Hydroxy-5Aα,9-Dimethyl-3-Methylene-2-Oxonaphtho[1,2-B]Furan-4α-Yl Ester is a complex, high-purity organic ester with a defined stereochemistry, serving as a critical chiral building block in advanced synthesis. Its value lies in enabling the construction of sophisticated molecular architectures with precise spatial orientation, which is paramount for developing compounds with targeted biological activity. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for projects involving novel active ingredients and natural product derivatives.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in oncology, anti-infective, and neurological therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry is required for efficacy and environmental selectivity.
• Natural Product Analog Synthesis: Serves as a building block for synthesizing analogs of complex natural products for structure-activity relationship (SAR) studies.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development and testing of new asymmetric catalytic methodologies.
• Fine Chemical Production: Utilized in the multi-step synthesis of other high-value, specialty fine chemicals and flavors & fragrances.
• Academic & Institutional Research: A valuable compound for chemical research in universities and institutes focusing on synthetic methodology and medicinal chemistry.

Basic Information

Product Name	(Z)-2-(Hydroxymethyl)-2-Butenoic Acid (3Ar)-2,3,3Aβ,4,5,5A,6,7,9Aβ,9Bα-Decahydro-6α-Hydroxy-5Aα,9-Dimethyl-3-Methylene-2-Oxonaphtho[1,2-B]Furan-4α-Yl Ester
CAS No.	92356-86-0
Molecular Formula	C20H28O6
Molecular Weight	364.44 g/mol
Synonyms	(Z)-2-(Hydroxymethyl)but-2-enoic acid (3aR,4S,5aR,6R,9aS,9bR)-decahydro-6-hydroxy-5a,9-dimethyl-3-methylene-2-oxonaphtho[1,2-b]furan-4-yl ester; 2-Butenoic acid, 2-(hydroxymethyl)-, (3aR,4S,5aR,6R,9aS,9bR)-decahydro-6-hydroxy-5a,9-dimethyl-3-methylene-2-oxonaphtho[1,2-b]furan-4-yl ester, (Z)-; CAS 92356-86-0; (Z)-2-(Hydroxymethyl)-2-butenoic acid ester with a decahydro naphthofuranone derivative.
EINECS	Contact for details

Quality Control

Our (Z)-2-(Hydroxymethyl)-2-Butenoic Acid Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure identity, strength, quality, and purity. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and R&D documentation needs. Specifications are aligned with the stringent requirements of pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.