Description

Ethyl 3-Bromo-2-Hydroxypropanoate is a versatile brominated hydroxy ester, a key chiral building block in organic synthesis. This compound is valued for its bifunctional reactivity, allowing for selective transformations at both the bromo and hydroxy groups. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of chiral drugs, particularly β-blockers and other cardiovascular agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Chiral Building Block: Serves as a starting material for the preparation of other enantiomerically pure compounds via nucleophilic substitution or ring-opening reactions.
• Polymer Modification: Can be incorporated into polymer chains to introduce functional groups for cross-linking or to impart specific material properties.
• Chemical Research: Employed in academic and industrial R&D for methodological development in asymmetric synthesis and catalysis.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances requiring precise molecular architecture.

Basic Information

Product Name	Ethyl 3-Bromo-2-Hydroxypropanoate
CAS No.	92234-23-6
Molecular Formula	C5H9BrO3
Molecular Weight	197.03 g/mol
Synonyms	Ethyl 3-bromo-2-hydroxypropionate; 2-Hydroxy-3-bromopropionic Acid Ethyl Ester; 3-Bromo-2-hydroxypropionic Acid Ethyl Ester; Ethyl 3-Bromo-2-hydroxypropionate; Ethyl DL-3-Bromo-2-hydroxypropanoate; (±)-Ethyl 3-bromo-2-hydroxypropanoate; Ethyl β-Bromo-α-hydroxypropionate; NSC 404087
EINECS	Contact for details

Quality Control

Our Ethyl 3-Bromo-2-Hydroxypropanoate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.