Description

Acridinium, 10-(6-((2-Aminoethyl)Amino)Hexyl)-3,6-Bis(Dimethylamino)-, Chloride, Tetrahydrochloride is a specialized cationic dye derivative with a polyamine linker, offering unique photophysical and binding properties. This compound is valued for its ability to intercalate with nucleic acids and serve as a versatile scaffold for developing diagnostic and research probes. It is primarily required by manufacturers and research institutions in the fields of molecular biology, diagnostic assay development, and advanced materials science.

Application

• Fluorescent Probes & Stains: Used as a core structure for developing sensitive fluorescent dyes for DNA/RNA detection and cell imaging.
• Diagnostic Reagents: A key intermediate in the synthesis of chemiluminescent or fluorescent labels for immunoassays and clinical diagnostics.
• Bioconjugation: The amine-functionalized linker allows for covalent attachment to antibodies, proteins, or nanoparticles for targeted delivery and sensing.
• Photodynamic Therapy (PDT) Research: Investigated as a potential photosensitizer precursor due to its acridine core and light-absorbing properties.
• Material Science: Employed in the development of photoactive polymers and sensors where its cationic and chromophoric characteristics are beneficial.
• Biochemical Research: Serves as a tool compound for studying nucleic acid structure, protein interactions, and enzyme mechanisms.

Basic Information

Product Name	Acridinium, 10-(6-((2-Aminoethyl)Amino)Hexyl)-3,6-Bis(Dimethylamino)-, Chloride, Tetrahydrochloride
CAS No.	92220-84-3
Molecular Formula	C25H44ClN5 • 4HCl
Molecular Weight	Approx. 603.9 g/mol (Tetrahydrochloride salt)
Synonyms	10-(6-((2-Aminoethyl)amino)hexyl)-3,6-bis(dimethylamino)acridinium chloride tetrahydrochloride; N-[6-[(2-Aminoethyl)amino]hexyl]-3,6-bis(dimethylamino)acridinium chloride tetrahydrochloride; Acridine Orange derivative with spermine linker; Cationic Acridine Orange homodimer precursor; Fluorescent acridinium polyamine salt; Acridinium dye, aminoalkyl-substituted; Lumi4-Tb cryptate synthesis intermediate; Diagnostic dye intermediate 92220-84-3.
EINECS	Contact for details

Quality Control

Our production of this high-purity biochemical intermediate adheres to stringent quality protocols. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and other critical parameters is provided with each shipment to ensure it meets your specific research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Orange to red solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.