Description

tert-Butyl 3-Aminobenzoate is a versatile chemical intermediate featuring both a protected carboxylic acid group and a reactive aromatic amine. This compound is valued for its role in facilitating complex organic syntheses, particularly in the construction of pharmaceutical and agrochemical active ingredients. It is primarily sought by research and development chemists, as well as process development teams, in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of amides, peptides, and other functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a benzoic acid derivative with an amine handle.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides where the tert-butyl ester group offers advantageous stability during synthesis.
• Peptide Mimetics & Conjugation: Serves as a precursor for creating peptide analogs or for coupling reactions to attach fluorophores or other tags in bioconjugation.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex organic molecules, leveraging the orthogonal reactivity of the amine and protected acid groups.
• Material Science Precursor: Potential monomer or modifying agent in the synthesis of specialty polymers and advanced materials.

Basic Information

Product Name	tert-Butyl 3-Aminobenzoate
CAS No.	92146-82-2
Molecular Formula	C11H15NO2
Molecular Weight	193.24 g/mol
Synonyms	3-Aminobenzoic Acid tert-Butyl Ester; Benzoic acid, 3-amino-, 1,1-dimethylethyl ester; tert-Butyl m-aminobenzoate; 3-(tert-Butoxycarbonyl)aniline; m-Aminobenzoic Acid tert-Butyl Ester; BOC-Aniline-3-carboxylic Acid (common misnomer); 1,1-Dimethylethyl 3-aminobenzoate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Aminobenzoate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.