Description

(2S)-Boc-2-Amino-5-Hexenoic Acid Methyl Ester is a high-purity, chiral amino acid derivative featuring both a Boc-protected amine and a terminal alkene functional group. This compound is a critical building block in the synthesis of complex peptides and peptidomimetics, enabling the introduction of structural diversity and enabling further chemical modifications. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for developing novel therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) and peptide-based drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate non-natural amino acids with an orthogonal protecting group strategy.
• Chemical Biology Probes: Serves as a precursor for creating labeled or tagged amino acids used in proteomics and molecular imaging studies.
• Cross-Coupling Reactions: The terminal alkene moiety allows for further functionalization via metathesis or other cross-coupling methodologies.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Academic & Industrial Research: A valuable reagent for exploring new synthetic methodologies and constructing complex molecular architectures.

Basic Information

Product Name	(2S)-Boc-2-Amino-5-Hexenoic Acid Methyl Ester
CAS No.	92136-57-7
Molecular Formula	C₁₂H₂₁NO₄
Molecular Weight	243.30 g/mol
Synonyms	Methyl (2S)-2-[(tert-butoxycarbonyl)amino]hex-5-enoate; (S)-Methyl 2-((tert-butoxycarbonyl)amino)hex-5-enoate; Boc-L-2-Amino-5-hexenoic Acid Methyl Ester; (S)-Boc-2-Amino-5-hexenoic Acid Methyl Ester; L-Boc-2-Amino-5-hexenoic Acid Methyl Ester; Methyl (S)-2-(Boc-amino)hex-5-enoate; Boc-AHME; Boc-δ²-Hex-Gly-OMe
EINECS	Contact for details

Quality Control

Our (2S)-Boc-2-Amino-5-Hexenoic Acid Methyl Ester is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.