Description

(S)-2-(1-Hydroxy-1-Methylethyl) Pyrrolidine is a high-purity, chiral pyrrolidine derivative that serves as a critical building block in asymmetric synthesis. Its value lies in its ability to act as a versatile chiral auxiliary or ligand, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients with high stereoselectivity. CAS NO 92053-25-3.

Application

• Pharmaceutical Intermediates: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Catalysis: Used as a ligand or catalyst component in enantioselective hydrogenation, alkylation, and other C-C bond-forming reactions.
• Chiral Auxiliary: Employed to control stereochemistry in complex multi-step organic syntheses, ensuring high enantiomeric excess (ee) in the final product.
• Agrochemical Synthesis: Building block for developing chiral herbicides, fungicides, and plant growth regulators with improved efficacy and environmental profile.
• Academic & Industrial Research: Valuable reagent for methodological development in organic chemistry and for exploring new reaction pathways.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals, flavors, fragrances, and advanced materials requiring specific chirality.

Basic Information

Product Name	(S)-2-(1-Hydroxy-1-Methylethyl) Pyrrolidine
CAS No.	92053-25-3
Molecular Formula	C7H15NO
Molecular Weight	129.20 g/mol
Synonyms	(S)-2-(2-Hydroxypropan-2-yl)pyrrolidine; (S)-2-(1-Hydroxy-1-methylethyl)pyrrolidine; (S)-2-(2-Hydroxy-2-propyl)pyrrolidine; L-2-(1-Hydroxy-1-methylethyl)pyrrolidine; (S)-2-(α-Hydroxyisopropyl)pyrrolidine; (S)-2-(2-Hydroxyisopropyl)pyrrolidine; (S)-2-(1-Hydroxy-1-methyl-ethyl)-pyrrolidine; Pyrrolidine, 2-(1-hydroxy-1-methylethyl)-, (2S)-
EINECS	Contact for details

Quality Control

Our (S)-2-(1-Hydroxy-1-Methylethyl) Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with high-grade standards suitable for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.