Description

Spiro[3.5]Nonane-2-Carboxylic Acid is a specialized spirocyclic carboxylic acid building block valued for its unique three-dimensional structure and functional handle. This compound is critical for advanced research and development in medicinal chemistry, where it is used to modulate the physicochemical properties and conformational rigidity of novel drug candidates. It is primarily sought by pharmaceutical R&D teams, agrochemical innovators, and academic researchers focused on synthesizing complex molecules for high-value applications.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Medicinal Chemistry Research: Used in fragment-based drug discovery and lead optimization to introduce steric constraints and improve metabolic stability.
• Agrochemical Synthesis: Employed in the development of novel herbicides and fungicides, where its spirocyclic core can enhance biological activity.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal and mechanical properties.
• Ligand and Catalyst Development: Utilized to create novel chiral ligands for asymmetric catalysis in fine chemical synthesis.
• Academic & Institutional Research: A valuable reagent for methodological studies in organic synthesis and stereochemistry.

Basic Information

Product Name	Spiro[3.5]Nonane-2-Carboxylic Acid
CAS No.	92015-84-4
Molecular Formula	C10H14O2
Molecular Weight	166.22 g/mol
Synonyms	2-Spiro[3.5]nonanecarboxylic acid; 2-Carboxyspiro[3.5]nonane; Spiro[3.5]nonane-2-carboxylic acid; 2-Spiro(3,5)nonanecarboxylic acid; 92015-84-4; Spiro(3.5)nonane-2-carboxylic acid; Spiro[3,5]nonane-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our Spiro[3.5]Nonane-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.