Description

n-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Methylideneamino]-7-Ethoxy-2-Methyl-Quinolin-4-Amine is a sophisticated nitrogen mustard derivative quinoline compound, primarily valued as a key intermediate in advanced pharmaceutical research and development. Its complex molecular architecture, featuring both a quinoline scaffold and a bis(2-chloroethyl)amino group, makes it a critical building block for synthesizing targeted therapeutic agents. This high-purity intermediate is essential for researchers and manufacturers in the oncology and medicinal chemistry sectors, where precise molecular construction is paramount for developing novel drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel nitrogen mustard-based chemotherapeutic agents and targeted cancer therapies.
• Medicinal Chemistry Research: Used as a specialized building block in drug discovery programs focused on alkylating agents and DNA-interactive compounds.
• Oncology Drug Development: Employed in R&D for creating potential anti-cancer compounds that leverage the quinoline structure for improved targeting or pharmacokinetics.
• Biochemical Tool Compound: Acts as a model compound in studies investigating the mechanism of action of alkylating agents and their interactions with biological targets.
• High-Value Fine Chemical Synthesis: Utilized in multi-step organic synthesis for producing complex, high-value molecules for clinical and pre-clinical evaluation.

Basic Information

Product Name	n-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Methylideneamino]-7-Ethoxy-2-Methyl-Quinolin-4-Amine
CAS No.	91919-70-9
Molecular Formula	C23H26Cl2N4O
Molecular Weight	453.39 g/mol
Synonyms	7-Ethoxy-N-[(4-{[bis(2-chloroethyl)amino]phenyl})methylideneamino]-2-methylquinolin-4-amine; 4-Amino-7-ethoxy-2-methylquinoline nitrogen mustard derivative; N-(4-(Bis(2-chloroethyl)amino)benzylidene)-7-ethoxy-2-methylquinolin-4-amine; Quinoline nitrogen mustard intermediate; 91919-70-9; Mustard-quinoline hybrid compound
EINECS	Contact for details

Quality Control

Every batch of our n-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Methylideneamino]-7-Ethoxy-2-Methyl-Quinolin-4-Amine is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, impurities, and full analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, prolonged exposure to light, air, or elevated temperatures should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.