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n-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Methylideneamino]-6-Methoxy-2-Me Thyl-Quinolin-4-Amine CAS NO 91919-67-4


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CAS No.:91919-67-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Methylideneamino]-6-Methoxy-2-Methyl-Quinolin-4-Amine is a specialized nitrogen mustard derivative quinoline compound with significant research and development potential. This molecule matters for its structural complexity, which combines a DNA-alkylating nitrogen mustard moiety with a quinoline scaffold, a feature of interest in advanced pharmaceutical and biochemical studies. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing novel therapeutic agents, particularly in oncology and targeted drug delivery systems.

Application

  • Pharmaceutical Research & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel chemotherapeutic agents and targeted cancer therapies.
  • Biochemical Probe Development: Used in academic and industrial research to study DNA alkylation mechanisms, cell cycle inhibition, and apoptosis pathways.
  • Antineoplastic Agent Synthesis: Acts as a critical building block for the preparation of nitrogen mustard-based compounds with potential antitumor activity.
  • Medicinal Chemistry Libraries: Incorporated into compound libraries for high-throughput screening (HTS) to identify new lead structures for drug discovery programs.
  • Fine Chemical Intermediate: Employed in the custom synthesis of complex, high-value molecules for specialized client requirements in the life sciences sector.

Basic Information

Item Details
Product Name n-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Methylideneamino]-6-Methoxy-2-Methyl-Quinolin-4-Amine
CAS No. 91919-67-4
Molecular Formula C22H24Cl2N4O
Molecular Weight 431.36 g/mol
Synonyms 4-[[[4-[Bis(2-chloroethyl)amino]phenyl]methylene]amino]-6-methoxy-2-methylquinoline; 6-Methoxy-2-methyl-4-[[[4-[bis(2-chloroethyl)amino]phenyl]methylene]amino]quinoline; NSC 339539; Quinoline, 4-[[[4-[bis(2-chloroethyl)amino]phenyl]methylene]amino]-6-methoxy-2-methyl-; 4-((4-(Bis(2-chloroethyl)amino)benzylidene)amino)-6-methoxy-2-methylquinoline
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Quality Control

Our production of n-[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Methylideneamino]-6-Methoxy-2-Methyl-Quinolin-4-Amine adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our quality system is designed to meet the exacting standards required for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store in accordance with all applicable local and international regulations for hazardous chemicals.

Specification

Item Specification
Appearance Yellow to light brown powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 97.0%
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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