Description

Homocitric Acid-γ-Lactone is a specialized lactone derivative of homocitric acid, serving as a key chiral intermediate and building block in advanced organic synthesis. Its unique structure makes it valuable for constructing complex molecules with specific stereochemistry. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and studying biochemical pathways.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the research and development of new drug candidates, particularly for compounds targeting metabolic enzymes.
• Biochemical Research: Used as a reference standard or probe in enzymatic studies and metabolic pathway analysis, especially related to citrate and homocitrate cycles.
• Fine Chemical Synthesis: Acts as a versatile building block for the synthesis of complex natural product analogs, flavors, and fragrances requiring specific lactone motifs.
• Agrochemical Development: Employed in the research phase for creating novel, biologically active molecules with potential herbicidal or fungicidal properties.
• Academic Research: Utilized in university and institutional laboratories for methodological development in asymmetric synthesis and stereochemistry studies.

Basic Information

Product Name	Homocitric Acid-γ-Lactone
CAS No.	91912-46-8
Molecular Formula	C7H10O5
Molecular Weight	174.15 g/mol
Synonyms	Homocitric acid γ-lactone; 2-Hydroxy-1,2,4-butanetricarboxylic acid 1,4-lactone; 3-Carboxy-3-hydroxypentane-1,5-dioic acid 1,4-lactone; (3S)-3-Carboxy-3-hydroxypentanedioic acid 1,4-lactone; L-Homocitric acid γ-lactone; Homocitric acid 1,4-lactone
EINECS	Contact for details

Quality Control

Our Homocitric Acid-γ-Lactone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, identity confirmation by IR and NMR spectroscopy, and determination of chemical purity. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.