Description

[1R,(-)]-6α-Acetyloxy-1,2,4Aα,5,6,8Aα-Hexahydro-4,7-Dimethyl-α-Methylene-1α-Naphthaleneacetic Acid Methyl Ester is a high-purity, chiral synthetic intermediate of significant interest in advanced organic synthesis. Its complex, functionalized decalin structure makes it a valuable building block for the development of novel bioactive compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to create stereochemically defined molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel therapeutic agents, particularly for complex natural product derivatives.
• Agrochemical Research: Used in the development of new, stereoselective pesticides and herbicides where specific spatial configuration is critical for activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex polycyclic frameworks and testing new synthetic methodologies.
• Asymmetric Catalysis Studies: Serves as a sophisticated substrate for evaluating new chiral catalysts and reaction conditions.
• Reference Standard: Used as an analytical standard for quality control and method development in laboratories producing or researching similar compounds.

Basic Information

Product Name	[1R,(-)]-6α-Acetyloxy-1,2,4Aα,5,6,8Aα-Hexahydro-4,7-Dimethyl-α-Methylene-1α-Naphthaleneacetic Acid Methyl Ester
CAS No.	91896-98-9
Molecular Formula	C19H26O4
Molecular Weight	318.41 g/mol
Synonyms	(-)-6α-Acetoxy-4,7-dimethyl-α-methylene-1α-naphthaleneacetic acid methyl ester; (1R)-6α-Acetyloxy-1,2,4aα,5,6,8aα-hexahydro-4,7-dimethyl-α-methylene-1-naphthaleneacetic acid methyl ester; Methyl (1R)-6α-acetoxy-4,7-dimethyl-α-methylidene-1,2,4a,5,6,8a-hexahydro-1-naphthaleneacetate; Methyl (1R)-6α-acetoxy-4,7-dimethyl-α-methylidene-1,2,4a,5,6,8a-hexahydro-1-naphthaleneacetate; 1R-6α-Acetoxy-4,7-dimethyl-α-methylene-1α-naphthaleneacetic acid methyl ester
EINECS	Contact for details

Quality Control

Our [1R,(-)]-6α-Acetyloxy-1,2,4Aα,5,6,8Aα-Hexahydro-4,7-Dimethyl-α-Methylene-1α-Naphthaleneacetic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.