Description

2'-Hydroxy-3,4,6'-Trimethoxychalcone is a specialized chalcone derivative, a class of organic compounds known for their diverse biological activities. This compound is valued as a key synthetic intermediate and a promising scaffold for research into novel bioactive molecules. It is primarily sought by the pharmaceutical, biotechnology, and fine chemical industries for applications in drug discovery, medicinal chemistry research, and as a reference standard.

Application

• Pharmaceutical Research & Development: Serves as a core scaffold for synthesizing and screening new drug candidates, particularly in areas like anti-inflammatory, anticancer, and antimicrobial agents.
• Medicinal Chemistry Studies: Used as a reference compound or intermediate to study structure-activity relationships (SAR) of chalcone derivatives.
• Biochemical Research: Employed in in-vitro assays to investigate biological pathways, enzyme inhibition, and cellular mechanisms.
• Fine Chemical Synthesis: Acts as a versatile building block for the synthesis of more complex heterocyclic compounds and natural product analogs.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2'-Hydroxy-3,4,6'-Trimethoxychalcone
CAS No.	91856-16-5
Molecular Formula	C₁₈H₁₈O₆
Molecular Weight	330.33 g/mol
Synonyms	2'-Hydroxy-3,4,6'-trimethoxychalcone; (E)-1-(2-Hydroxyphenyl)-3-(3,4,6-trimethoxyphenyl)prop-2-en-1-one; 3,4,6-Trimethoxy-2'-hydroxychalcone; NSC 407347; Chalcone, 2'-hydroxy-3,4,6'-trimethoxy-; 1-(2-Hydroxyphenyl)-3-(3,4,6-trimethoxyphenyl)-2-propen-1-one
EINECS	Contact for details

Quality Control

Our 2'-Hydroxy-3,4,6'-Trimethoxychalcone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for materials intended for research use in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.