Description

1,3-Benzenedicarboxylic Acid, 1,3-Bis(2,5-Dioxo-1-Pyrrolidinyl) Ester is a high-purity, reactive chemical intermediate designed for advanced synthesis. This compound is valued for its dual activated ester functionality, which enables efficient and selective coupling reactions under mild conditions. It is primarily sought by manufacturers in the pharmaceutical, polymer, and specialty chemical industries for the development of novel active ingredients, high-performance resins, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and prodrugs via amide bond formation.
• Polymer Crosslinking Agent: Used in the production of thermosetting resins, epoxy hardeners, and high-strength composite materials.
• Peptide Synthesis Reagent: Serves as an efficient coupling agent in solid-phase and solution-phase peptide synthesis.
• Bioconjugation Linker: Facilitates the stable attachment of dyes, tags, or drug molecules to proteins, antibodies, or nanoparticles for diagnostics and therapeutics.
• Specialty Chemical Synthesis: Intermediate for creating custom diamides, polyamides, and other functionalized aromatic compounds.
• Adhesive & Coating Formulations: Imparts enhanced adhesion and durability in advanced industrial coating systems.

Basic Information

Product Name	1,3-Benzenedicarboxylic Acid, 1,3-Bis(2,5-Dioxo-1-Pyrrolidinyl) Ester
CAS No.	91779-84-9
Molecular Formula	C16H12N2O8
Molecular Weight	360.28 g/mol
Synonyms	Isophthalic Acid Bis(N-hydroxysuccinimide) Ester; Isophthalic Acid Di(NHS) Ester; 1,3-Bis(2,5-dioxopyrrolidin-1-yl)oxycarbonylbenzene; Isophthaloyl Bis(N-succinimidyl) Ester; NHS-Activated Isophthalate; 1,3-Phenylenedicarboxylic Acid Bis(2,5-dioxo-1-pyrrolidinyl) Ester; 1,3-Bis(succinimidyloxycarbonyl)benzene; Di(N-succinimidyl) Isophthalate
EINECS	Contact for details

Quality Control

Our production of 1,3-Benzenedicarboxylic Acid, 1,3-Bis(2,5-Dioxo-1-Pyrrolidinyl) Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions, such as in a desiccator or under an inert atmosphere, to prevent hydrolysis and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.