Description

2-Bromo-6-Chloro-3-Nitropyridine is a versatile and high-purity halogenated nitropyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the nitropyridine core provides specific biological activity.
• Material Science Research: Serves as a building block for creating functionalized ligands, organic semiconductors, and other specialty materials.
• Cross-Coupling Reactions: The bromo and chloro substituents make it an excellent substrate for selective Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Nucleophilic Aromatic Substitution: The activated nitro and halogen groups allow for sequential functionalization, enabling the creation of diverse chemical libraries.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting methodological studies and exploring new chemical spaces.

Basic Information

Product Name	2-Bromo-6-Chloro-3-Nitropyridine
CAS No.	91678-23-8
Molecular Formula	C5H2BrClN2O2
Molecular Weight	237.44 g/mol
Synonyms	2-Bromo-6-chloro-3-nitropyridine; 6-Chloro-2-bromo-3-nitropyridine; 3-Nitro-2-bromo-6-chloropyridine; 2-Bromo-6-chloro-3-nitro-pyridine; Pyridine, 2-bromo-6-chloro-3-nitro-; 91678-23-8; BCPN
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Chloro-3-Nitropyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.