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n-(7-Nitro-2,1,3-Benzoxadiazol-4-Yl)Dioleoylphosphatidylethanolamine CAS NO 91632-07-4


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CAS No.:91632-07-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-(7-Nitro-2,1,3-Benzoxadiazol-4-Yl)Dioleoylphosphatidylethanolamine is a specialized, fluorescently labeled phospholipid derivative. This compound is engineered for advanced research and diagnostic applications, offering a powerful tool for membrane studies and biomolecule tracking. It is essential for scientists and developers in the life sciences, pharmaceutical research, and diagnostic reagent manufacturing sectors who require precise, high-quality fluorescent probes.

Application

  • Fluorescent Labeling of Biomembranes: Used as a fluorescent probe to study lipid bilayer dynamics, membrane fusion, and cellular uptake mechanisms.
  • Liposome and Nanoparticle Tracking: Incorporated into liposomal formulations and drug delivery nanoparticles for in vitro and in vivo tracking via fluorescence microscopy or spectroscopy.
  • Biochemical Assay Development: Serves as a critical component in developing fluorescence-based assays for enzyme activity (e.g., phospholipases) or protein-lipid interactions.
  • Cell Biology Research: Applied in fluorescence imaging to visualize intracellular lipid trafficking and organelle membranes.
  • Diagnostic Reagent Manufacturing: Utilized in the production of fluorescent diagnostic kits and reagents for clinical and research laboratories.
  • Model Membrane Systems: Employed in the construction of artificial membranes and vesicles for biophysical studies.

Basic Information

Product Name n-(7-Nitro-2,1,3-Benzoxadiazol-4-Yl)Dioleoylphosphatidylethanolamine
CAS No. 91632-07-4
Molecular Formula C71H115N4O11P
Molecular Weight 1191.68 g/mol
Synonyms NBD-DOPE; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-1,3-benzoxadiazol-4-yl); N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine; DOPE-NBD; Fluorescent DOPE; NBD PE; 18:1 NBD PE; Nitrobenzoxadiazole-labeled phosphatidylethanolamine
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Quality Control

Our n-(7-Nitro-2,1,3-Benzoxadiazol-4-Yl)Dioleoylphosphatidylethanolamine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive research applications. Certificates of Analysis (COA) detailing lot-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and performance. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item Specification
Appearance Yellow to orange solid or film
Identification (HPLC/UV) Conforms to reference standard
Purity (HPLC) ≥ 98.0%
Solubility Soluble in chloroform, DMSO, ethanol
Fluorescence Properties Excitation ~460 nm, Emission ~534 nm (in methanol)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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