Description

1H-Tetrazole-5-Carboxylicacid,1-Methyl-,Ethylester(9Ci) is a specialized heterocyclic organic compound belonging to the tetrazole class, serving as a versatile building block in advanced chemical synthesis. Its core value lies in its role as a key precursor for generating tetrazole-based pharmacophores and energetic materials, where the ester functionality allows for further derivatization. This high-purity intermediate is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, particularly for creating compounds with specific biological activity or tailored physical properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing tetrazole rings, such as certain sartans (angiotensin II receptor blockers).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the tetrazole moiety can enhance biological activity and stability.
• Energetic Materials Research: Serves as a building block for synthesizing high-energy-density materials (HEDMs) and propellant additives due to the high nitrogen content of the tetrazole ring.
• Coordination Chemistry & Ligand Design: Acts as a precursor for polydentate ligands used in catalysis and the formation of metal-organic frameworks (MOFs).
• Polymer Modification: Employed to introduce tetrazole functional groups into polymer backbones, altering material properties like thermal stability and reactivity.
• Chemical Biology & Proteomics: Utilized in click chemistry and bioorthogonal reactions for labeling and studying biological systems.

Basic Information

Product Name	1H-Tetrazole-5-Carboxylicacid,1-Methyl-,Ethylester(9Ci)
CAS No.	91616-41-0
Molecular Formula	C5H8N4O2
Molecular Weight	156.14 g/mol
Synonyms	1-Methyl-1H-tetrazole-5-carboxylic acid ethyl ester; Ethyl 1-methyl-1H-tetrazole-5-carboxylate; 1-Methyl-5-ethoxycarbonyltetrazole; 5-(Ethoxycarbonyl)-1-methyl-1H-tetrazole; 1-Methyl-1H-tetrazole-5-carboxylic acid ethyl ester (9CI); NSC 403079; 1-Methyl-5-carbethoxytetrazole
EINECS	Contact for details

Quality Control

Our 1H-Tetrazole-5-Carboxylicacid,1-Methyl-,Ethylester(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.