Description

2,4,6-Trimethoxypyridine is a versatile methoxy-substituted pyridine derivative that serves as a key synthetic intermediate in advanced organic chemistry. Its value lies in its unique substitution pattern, which provides a sterically hindered and electron-rich aromatic system for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its pyridine core contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis for fine chemical synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or photoactive components.
• Chemical Research & Development: A valuable scaffold in medicinal and process chemistry for structure-activity relationship (SAR) studies and route scouting.

Basic Information

Product Name	2,4,6-Trimethoxypyridine
CAS No.	91591-88-7
Molecular Formula	C8H11NO3
Molecular Weight	169.18 g/mol
Synonyms	2,4,6-Trimethoxypyridine; Pyridine, 2,4,6-trimethoxy-; 2,4,6-Trimethoxy-pyridine; 1,3,5-Trimethoxypyridine (common misnomer); TMPy; NSC 403914; 2,4,6-TMP
EINECS	Contact for details

Quality Control

Our 2,4,6-Trimethoxypyridine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and relevant ICH guidelines ensures a reliable supply for research and development as well as scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.