Description

2-Chloro-4,5,6-Trimethylnicotinonitrile is a versatile and highly functionalized pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of reactive sites—the chloro and nitrile groups—which enable precise molecular construction for complex target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex drug candidates, particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides due to its functionalized heterocyclic core.
• Material Science Research: Serves as a precursor for creating specialized ligands, catalysts, and functional polymers with tailored electronic properties.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for high-value, low-volume specialty chemicals.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis and heterocyclic chemistry within university and industrial research laboratories.

Basic Information

Product Name	2-Chloro-4,5,6-Trimethylnicotinonitrile
CAS No.	91591-64-9
Molecular Formula	C9H9ClN2
Molecular Weight	180.63 g/mol
Synonyms	2-Chloro-4,5,6-trimethyl-3-pyridinecarbonitrile; 2-Chloro-4,5,6-trimethylnicotinonitrile; 3-Cyano-2-chloro-4,5,6-trimethylpyridine; 2-Chloro-4,5,6-trimethyl-3-cyanopyridine; Nicotinonitrile, 2-chloro-4,5,6-trimethyl-; 91591-64-9
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4,5,6-Trimethylnicotinonitrile is produced and tested under a strict quality management system to ensure consistency and reliability for your synthetic processes. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing full transparency on purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.