Description

2-Hydroxy-4,5,6-Trimethylnicotinonitrile is a versatile and high-value heterocyclic nitrile building block. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, due to its functionalized pyridine core. It is primarily sought after by research institutions and industrial manufacturers engaged in developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system or acting as enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Chemical Research & Development: A valuable building block for medicinal chemistry and process chemistry research in both academic and industrial settings.

Basic Information

Product Name	2-Hydroxy-4,5,6-Trimethylnicotinonitrile
CAS No.	91591-59-2
Molecular Formula	C9H10N2O
Molecular Weight	162.19 g/mol
Synonyms	2-Hydroxy-4,5,6-trimethyl-3-pyridinecarbonitrile; 4,5,6-Trimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile; 3-Cyano-4,5,6-trimethyl-2(1H)-pyridinone; 2-Hydroxy-4,5,6-trimethylnicotinamide nitrile (precursor); 4,5,6-Trimethyl-2-pyridone-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-4,5,6-Trimethylnicotinonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.