Description

2-((tert-Butyldiphenylsilyl)Oxy)Ethanamine is a versatile organosilicon-protected amine building block, primarily used as a key intermediate in advanced organic synthesis. Its value lies in the tert-butyldiphenylsilyl (TBDPS) protecting group, which offers robust stability under a wide range of reaction conditions while allowing for selective deprotection. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for constructing complex molecules, such as active pharmaceutical ingredients (APIs) and natural products.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used for the protection of amine functionalities during solid-phase and solution-phase peptide synthesis.
• Natural Product Synthesis: Serves as a protected aminoethanol derivative in the total synthesis of complex natural products with biological activity.
• Agrochemical Research: Employed as an intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Acts as a functional precursor for modifying surfaces or creating silicon-containing polymers and dendrimers.
• Chemical Biology & Proteomics: Utilized in the preparation of probes, linkers, and reagents for studying biological systems.

Basic Information

Product Name	2-((tert-Butyldiphenylsilyl)Oxy)Ethanamine
CAS No.	91578-89-1
Molecular Formula	C18H25NOSi
Molecular Weight	299.49 g/mol
Synonyms	2-[(tert-Butyldiphenylsilyl)oxy]ethanamine; 2-(tert-Butyldiphenylsiloxy)ethylamine; N-(2-((tert-Butyldiphenylsilyl)oxy)ethyl)amine; 2-Aminoethoxy(tert-butyl)diphenylsilane; TBDPS-protected ethanolamine; Ethanolamine, O-(tert-butyldiphenylsilyl)-; Amino TBDPS ether; 91578-89-1
EINECS	Contact for details

Quality Control

Our 2-((tert-Butyldiphenylsilyl)Oxy)Ethanamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring reproducible results and supply chain reliability in R&D and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.