Description

2-Chlorothiazolo[5,4-b]pyridine is a high-value heterocyclic building block featuring a fused thiazole and pyridine ring system. This compound is essential for advanced organic synthesis, serving as a versatile precursor for the development of novel pharmaceuticals and agrochemicals. It is particularly sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting various disease pathways.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its unique heterocyclic structure for enhanced biological activity.
• Material Science Research: Serves as a building block for organic electronic materials, such as ligands for catalysts or components in organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Employed in the synthesis of molecular probes and inhibitors for studying enzyme function and biological mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up manufacturing under cGMP or ISO standards.

Basic Information

Product Name	2-Chlorothiazolo[5,4-b]pyridine
CAS No.	91524-96-8
Molecular Formula	C6H3ClN2S
Molecular Weight	170.62 g/mol
Synonyms	2-Chloro[1,3]thiazolo[5,4-b]pyridine; Thiazolo[5,4-b]pyridine, 2-chloro-; 2-Chlorothiazolo[5,4-b]pyridine; 91524-96-8; 2-Chloro-thiazolo[5,4-b]pyridine; 2-Chloro-1,3-thiazolo[5,4-b]pyridine
EINECS	Contact for details

Quality Control

Our 2-Chlorothiazolo[5,4-b]pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.