Description

3-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Pentanedioic Acid Diethyl Ester is a high-purity, protected diester intermediate of significant value in advanced organic synthesis. Its core utility lies in its role as a versatile building block for constructing complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. This compound is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Mimetics & Prodrug Synthesis: Used to introduce protected dicarboxylic acid functionalities into peptide backbones or as a linker in prodrug design.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer & Material Science: Acts as a monomer or cross-linking agent precursor for specialty polymers and functional materials.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	3-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Pentanedioic Acid Diethyl Ester
CAS No.	91424-39-4
Molecular Formula	C15H30O5Si
Molecular Weight	318.49 g/mol
Synonyms	Diethyl 3-[(tert-Butyldimethylsilyl)oxy]glutarate; 3-(tert-Butyldimethylsilyloxy)glutaric Acid Diethyl Ester; 3-[(Tert-Butyldimethylsilyl)oxy]pentanedioic Acid Diethyl Ester; Diethyl 3-((tert-Butyldimethylsilyl)oxy)pentanedioate; Glutaric acid, 3-[(1,1-dimethylethyl)dimethylsilyl]oxy]-, diethyl ester; TBDMS-protected Diethyl Glutarate; 3-TBDMS-O-Glutaric Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Our 3-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Pentanedioic Acid Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.