Description

6-Bromo-4-(Trifluoromethyl)Pyridin-2(1H)-One is a high-value, multi-functional pyridinone derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromo and trifluoromethyl substituents, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized ligands and organic electronic materials due to its halogen and fluorine content.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for biochemical and diagnostic research applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	6-Bromo-4-(Trifluoromethyl)Pyridin-2(1H)-One
CAS No.	91416-08-9
Molecular Formula	C6H3BrF3NO
Molecular Weight	241.99 g/mol
Synonyms	6-Bromo-4-(trifluoromethyl)-1,2-dihydropyridin-2-one; 6-Bromo-4-(trifluoromethyl)-2-pyridone; 2(1H)-Pyridinone, 6-bromo-4-(trifluoromethyl)-; 4-(Trifluoromethyl)-6-bromopyridin-2(1H)-one; 6-Bromo-4-trifluoromethyl-2(1H)-pyridinone; 6-Bromo-4-trifluoromethylpyridin-2-ol (tautomer); 91416-08-9 (CAS)
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-4-(Trifluoromethyl)Pyridin-2(1H)-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.