Description

4-(Hydroxymethyl)Benzyl-3 β-Cholestanyl Succinate is a high-purity, synthetic sterol derivative designed for advanced research and pharmaceutical development. This compound is valued for its unique molecular architecture, which combines a cholestanyl backbone with a functionalized benzyl succinate moiety, making it a versatile intermediate for creating novel drug candidates and bioactive molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for applications in targeted drug delivery systems, prodrug synthesis, and advanced material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel sterol-based prodrugs and active pharmaceutical ingredients (APIs).
• Lipid Nanoparticle (LNP) Research: Used in the formulation and development of advanced lipid-based delivery systems for nucleic acids (mRNA, siRNA) and other therapeutics.
• Bioconjugation & Prodrug Design: Serves as a linker or carrier molecule in antibody-drug conjugates (ADCs) and targeted prodrug strategies due to its functional hydroxymethyl group.
• Biomaterial & Polymer Science: A precursor for creating specialized polymers and coatings with bioactive or cholesterol-mimicking properties.
• Reference Standard: High-purity grade material for analytical method development, quality control, and regulatory submissions.
• Chemical Biology Research: Tool compound for studying cholesterol metabolism, membrane biology, and sterol-protein interactions.

Basic Information

Product Name	4-(Hydroxymethyl)Benzyl-3 β-Cholestanyl Succinate
CAS No.	91177-68-3
Molecular Formula	C45H72O5
Molecular Weight	693.06 g/mol
Synonyms	3β-Cholestanyl 4-(hydroxymethyl)benzyl succinate; Cholestan-3β-yl 4-(hydroxymethyl)benzyl succinate; 4-(Hydroxymethyl)benzyl 3β-cholestanyl succinate; 3β-Cholestanyl 4-(hydroxymethyl)phenylmethyl butanedioate; 4-(Hydroxymethyl)benzyl cholestan-3β-yl succinate; 91177-68-3; Cholestanyl benzyl succinate derivative
EINECS	Contact for details

Quality Control

Our 4-(Hydroxymethyl)Benzyl-3 β-Cholestanyl Succinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere or with desiccant after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.