Description

Ethyl 5-Nitro-1H-Indole-3-Carboxylate is a high-purity, versatile indole derivative serving as a critical building block in advanced organic synthesis. This compound matters because it provides a functionalized nitro-indole core essential for constructing complex molecules with potential biological activity. Pharmaceutical R&D and fine chemical manufacturers need it for developing new active pharmaceutical ingredients (APIs), agrochemicals, and specialty dyes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Research: Used in developing new generation pesticides and herbicides due to its bioactive indole scaffold.
• Material Science: Serves as a monomer or functional additive in the creation of advanced polymers and organic electronic materials.
• Academic & Industrial R&D: Essential reagent for medicinal chemistry programs and library synthesis in high-throughput screening.
• Dye & Pigment Synthesis: Intermediate for producing specialized nitro-substituted indole-based colorants.

Basic Information

Product Name	Ethyl 5-Nitro-1H-Indole-3-Carboxylate
CAS No.	91090-94-7
Molecular Formula	C11H10N2O4
Molecular Weight	234.21 g/mol
Synonyms	5-Nitro-1H-indole-3-carboxylic acid ethyl ester; Ethyl 5-nitroindole-3-carboxylate; 1H-Indole-3-carboxylic acid, 5-nitro-, ethyl ester; 3-Carbethoxy-5-nitroindole; 5-Nitroindole-3-carboxylic acid ethyl ester; Ethyl 5-nitro-1H-indole-3-carboxylate; 91090-94-7
EINECS	Contact for details

Quality Control

Our Ethyl 5-Nitro-1H-Indole-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) documenting all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.