Description

Cyclobutyl Isocyanide is a versatile organic building block characterized by its reactive isocyanide functional group attached to a cyclobutyl ring. This compound is of significant value in synthetic organic chemistry, particularly for its role in facilitating multi-component reactions and serving as a key precursor for heterocyclic and pharmaceutical intermediates. It is primarily sought after by research institutions and industrial R&D departments engaged in medicinal chemistry, agrochemical development, and advanced material science.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for constructing complex heterocyclic cores found in bioactive molecules.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging its reactivity to create novel active ingredients.
• Material Science Research: Employed in the creation of specialized polymers and ligands for catalytic systems, where the isocyanide group acts as a versatile linker.
• Multi-Component Reactions (MCRs): A key reagent in Passerini and Ugi-type reactions, enabling the efficient, one-pot synthesis of complex organic libraries for high-throughput screening.
• Ligand Synthesis for Catalysis: Serves as a building block for creating isocyanide-based ligands used in transition metal catalysis.
• Academic & Industrial R&D: Fundamental research tool in synthetic methodology development and exploratory chemistry projects.

Basic Information

Product Name	Cyclobutyl Isocyanide
CAS No.	90993-55-8
Molecular Formula	C5H7N
Molecular Weight	81.12 g/mol
Synonyms	Cyclobutylisonitrile; Isocyano-cyclobutane; Cyclobutane, isocyano-; Cyclobutyl isonitrile; Cyclobutylcarbylamine; 1-Isocyanocyclobutane
EINECS	Contact for details

Quality Control

Our Cyclobutyl Isocyanide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Due to its highly volatile and easily oxidized nature, it is recommended to store at 2-8°C for extended stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.