Description

1-(Triisopropylsilyl)Pyrrole-3-Carbaldehyde is a specialized organosilicon-protected pyrrole derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its core value lies in the triisopropylsilyl (TIPS) protecting group, which provides exceptional steric bulk and stability for selective functionalization of the pyrrole ring. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to construct complex heterocyclic scaffolds for active ingredient development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other heterocyclic-based therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides that require specific pyrrole motifs for biological activity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of conductive polymers and advanced organic electronic materials.
• Organic Synthesis Reagent: A versatile reagent for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) and other metal-mediated transformations due to its stable yet modifiable aldehyde group.
• Chemical Research & Development: Fundamental tool in academic and industrial R&D for exploring new reaction methodologies and constructing complex molecular architectures.

Basic Information

Product Name	1-(Triisopropylsilyl)Pyrrole-3-Carbaldehyde
CAS No.	90971-76-9
Molecular Formula	C15H27NOSi
Molecular Weight	265.47 g/mol
Synonyms	1-[(Triisopropylsilyl)]-1H-pyrrole-3-carboxaldehyde; 3-Formyl-1-(triisopropylsilyl)pyrrole; 1H-Pyrrole-3-carboxaldehyde, 1-(triisopropylsilyl)-; TIPS-Pyrrole-3-carbaldehyde; 1-TIPS-pyrrole-3-carbaldehyde; Pyrrole-3-carbaldehyde, 1-(triisopropylsilyl)-; 1-Triisopropylsilyl-1H-pyrrole-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 1-(Triisopropylsilyl)Pyrrole-3-Carbaldehyde is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and GC-MS, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere for prolonged procedures to ensure stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.