Description

Ethanone, 2-Bromo-1-(1H-Pyrrolo[2,3-B]Pyridin-3-Yl)- is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for oncology and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules, particularly kinase inhibitors and other targeted cancer therapies.
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in research laboratories.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for new chemical entities (NCEs) during API development.
• Biochemical Research: Serves as a tool compound for studying biological pathways and enzyme inhibition mechanisms in academic and industrial R&D settings.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	Ethanone, 2-Bromo-1-(1H-Pyrrolo[2,3-B]Pyridin-3-Yl)-
CAS No.	90929-73-0
Molecular Formula	C9H7BrN2O
Molecular Weight	239.07 g/mol
Synonyms	2-Bromo-1-(7-azaindol-3-yl)ethanone; 2-Bromo-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethan-1-one; 3-Acetyl-7-azaindole, 2-bromo derivative; 2-Bromo-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethanone; 1-(1H-Pyrrolo[2,3-b]pyridin-3-yl)-2-bromoethanone; 2-Bromo-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethan-1-one; 7-Azaindole-3-yl bromomethyl ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 2-Bromo-1-(1H-Pyrrolo[2,3-B]Pyridin-3-Yl)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding pharmaceutical applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.