Description

3-Amino-2,2,3,3-tetramethylpropionic acid methyl ester is a highly functionalized, sterically hindered amino acid derivative. This compound is valued for its role as a key chiral building block and intermediate in advanced organic synthesis, particularly for introducing the rigid, bulky 3-amino-2,2,3,3-tetramethylpropionyl (Atmp) moiety. It is essential for research and production in the pharmaceutical sector, where it is used to develop novel active pharmaceutical ingredients (APIs) and fine chemicals that require specific stereochemistry and enhanced stability.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex drug molecules, peptidomimetics, and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Serves as a building block for ligands, catalysts, and auxiliaries used in stereoselective chemical transformations.
• Peptide Chemistry: Used to incorporate sterically hindered, non-proteinogenic amino acid structures into peptide chains to modify stability and bioactivity.
• Agrochemical Research: An intermediate in the development of novel herbicides, fungicides, and plant growth regulators with tailored properties.
• Material Science: Potential monomer or modifier for creating specialized polymers with unique thermal or mechanical characteristics.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	3-Amino-2,2,3,3-tetramethylpropionic acid methyl ester
CAS No.	90886-53-6
Molecular Formula	C9H19NO2
Molecular Weight	173.25 g/mol
Synonyms	Methyl 3-amino-2,2,3,3-tetramethylpropanoate; 3-Amino-2,2,3,3-tetramethylpropanoic acid methyl ester; Atmp-OMe; 2,2,3,3-Tetramethyl-3-aminopropionic acid methyl ester; Methyl 3-amino-2,2,3,3-tetramethylpropionate; 3-Amino-2,2,3,3-tetramethylpropionate methyl ester; (3-Amino-2,2,3,3-tetramethylpropionyl) methyl ester
EINECS	Contact for details

Quality Control

Our 3-Amino-2,2,3,3-tetramethylpropionic acid methyl ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.