Description

n-Methyldeferrioxamine B is a chemically modified derivative of the potent iron-chelating agent deferoxamine (Desferal®). This compound is of significant interest in biochemical and pharmaceutical research for its altered metal-binding properties and pharmacokinetics. It serves as a critical research tool for scientists and developers in the fields of medicinal chemistry, metallobiology, and therapeutic chelator design. The product is supplied as a high-purity material suitable for laboratory and development-scale applications.

Application

• Biochemical Research: Used as a specific chelating agent to study iron metabolism, oxidative stress, and metal-mediated biological pathways.
• Medicinal Chemistry Development: Acts as a key intermediate or reference standard in the design and synthesis of novel therapeutic chelators for conditions like iron overload.
• Pharmaceutical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Cell Culture & Microbiology: Utilized in laboratory media to create defined, iron-limited conditions for studying microbial growth or cellular processes.
• Analytical Chemistry: Serves as a complexing agent in analytical methods for the detection and quantification of trace metals.

Basic Information

Product Name	n-Methyldeferrioxamine B
CAS No.	90846-21-2
Molecular Formula	C27H48N6O8
Molecular Weight	584.71 g/mol
Synonyms	N-Methyl Desferrioxamine B; N-Methyl Desferal; N-Methyl Deferoxamine; N-Methyl DFO-B; N-Methyl DFO; N-Methyl-1,17-diamino-9-aza-1,6,11,16-tetraoxoheptadecane; N-Methyl-N'-[5-[4-[5-(N-hydroxyacetamido)pentylamino]-4-oxobutanoyl]hydroxypentyl]butanediamide
EINECS	Contact for details

Quality Control

Our n-Methyldeferrioxamine B is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.