Description

L-Glutamic Acid, n-[4-[[ (2-Amino-1, 4-Dihydro-4-Oxo-6-Pteridinyl)Meth Yl]Methylamino]Benzoyl]- is a specialized folate derivative and a key biochemical intermediate. This compound is critical for research and development in metabolic pathways and enzymatic studies. It is primarily utilized by the pharmaceutical, biotechnology, and advanced life science research sectors for its role in one-carbon transfer reactions and as a precursor in the synthesis of more complex biomolecules.

Application

• Pharmaceutical Research & Development: As a critical intermediate in the synthesis of novel folate analogs and enzyme inhibitors for therapeutic applications.
• Biochemical Research: Used as a substrate or standard in enzymatic assays studying folate-dependent one-carbon metabolism.
• Nutritional Science Studies: Employed in research investigating advanced forms of vitamins and cofactors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in HPLC and LC-MS.
• Precursor Synthesis: A building block for the chemical synthesis of more complex, labeled, or conjugated folate molecules for diagnostic and research tools.

Basic Information

Product Name	L-Glutamic Acid, n-[4-[[ (2-Amino-1, 4-Dihydro-4-Oxo-6-Pteridinyl)Meth Yl]Methylamino]Benzoyl]-
CAS No.	2410-93-7
Molecular Formula	C₂₀H₂₃N₇O₇
Molecular Weight	473.45 g/mol
Synonyms	N-[4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid; 5-Methyl-5,6,7,8-tetrahydrofolic acid; 5-Methyltetrahydrofolate; 5-Methyl THF; 5-MTHF; 5-Methyl-5,6,7,8-tetrahydropteroyl-L-glutamate; Metafolin (brand name variant); Levomefolic acid
EINECS	Contact for details

Quality Control

Our L-Glutamic Acid, n-[4-[[ (2-Amino-1, 4-Dihydro-4-Oxo-6-Pteridinyl)Meth Yl]Methylamino]Benzoyl]- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.