Description

Calcium Disodium Edetate Dihydrate is a high-purity chelating agent widely recognized for its ability to sequester metal ions, thereby stabilizing formulations and enhancing product integrity. This compound is critical for ensuring quality and safety in applications where trace metal contamination can cause degradation, discoloration, or reduced efficacy. It is an essential raw material for manufacturers in the pharmaceutical, food & beverage, and personal care industries seeking reliable, compliant ingredients for their sensitive processes.

Application

• Pharmaceutical Stabilizer: Used as an active pharmaceutical ingredient (API) and excipient in injectable, ophthalmic, and topical formulations to chelate trace metals that catalyze oxidation.
• Food & Beverage Additive: Employed as a preservative and color/ flavor stabilizer (INS 385) in canned products, dressings, and soft drinks to prevent rancidity and maintain sensory qualities.
• Cosmetics & Personal Care: Acts as a chelating agent in creams, lotions, and shampoos to improve shelf life by inactivating metal ions that can degrade other ingredients.
• Industrial Processes: Utilized in water treatment, textile processing, and agrochemical formulations to control metal ion interference and improve process efficiency.
• Laboratory Reagent: Serves as a key component in analytical chemistry, buffer solutions, and cell culture media for its precise metal-binding properties.

Basic Information

Product Name	Calcium Disodium Edetate Dihydrate
CAS No.	23411-34-9
Molecular Formula	C10H12CaN2Na2O8 • 2H2O
Molecular Weight	410.31 g/mol
Synonyms	Calcium Disodium EDTA Dihydrate; Edetate Calcium Disodium Dihydrate; Calcium Disodium Ethylenediaminetetraacetate Dihydrate; (Ethylenedinitrilo)tetraacetic Acid Calcium Disodium Salt Dihydrate; Sequestrene NA2Ca; INS 385; E385; Calciate (Disodium) Dihydrate
EINECS	245-646-7

Quality Control

Our Calcium Disodium Edetate Dihydrate is manufactured under strict quality systems. It can be supplied to meet various pharmacopeial standards, including USP-NF, Ph. Eur., BP, and JP, as well as food-grade specifications like FCC. Every batch undergoes rigorous analytical testing to ensure identity, purity, and compliance with specified limits. A comprehensive Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which can lead to caking or degradation.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms
Assay (on dried basis)	97.0% - 102.0%
pH (5% solution)	6.5 - 8.0
Loss on Drying	8.0% - 11.0%
Heavy Metals	≤ 20 ppm
Iron (Fe)	≤ 50 ppm
Arsenic (As)	≤ 3 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.