Description

2-[2-[2-(2-Bromoacetyl)Oxyethoxy]Ethoxy]Ethyl 2-Bromoacetate is a specialized bifunctional alkylating agent featuring two reactive bromoacetate groups linked by a polyethylene glycol (PEG)-like spacer. This molecular structure matters for its ability to act as a versatile cross-linking reagent, enabling the precise conjugation of biomolecules or the synthesis of functionalized polymers and dendrimers. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for applications such as peptide modification, hydrogel formation, and the development of drug delivery systems.

Application

• Bioconjugation and Cross-linking: Used to covalently link proteins, peptides, or other biomolecules through reactive amine or thiol groups.
• Polymer Chemistry: Serves as a monomer or cross-linker in the synthesis of functionalized PEG-based polymers, hydrogels, and networks.
• Drug Delivery Systems: Employed in the fabrication of stimuli-responsive or biodegradable carrier matrices for controlled release.
• Surface Modification: Functionalizes surfaces (e.g., chips, nanoparticles) with reactive groups for subsequent biomolecule immobilization.
• Dendrimer and Macromolecule Synthesis: Acts as a building block for creating complex, branched molecular architectures.
• Affinity Chromatography Ligand Attachment: Used to attach specific ligands to chromatographic supports for purification processes.
• Diagnostic Reagent Development: Facilitates the labeling of antibodies or probes for assays and imaging.
• Material Science Research: Enables the study of structure-property relationships in novel synthetic materials.

Basic Information

Product Name	2-[2-[2-(2-Bromoacetyl)Oxyethoxy]Ethoxy]Ethyl 2-Bromoacetate
CAS No.	90783-55-4
Molecular Formula	C12H18Br2O8
Molecular Weight	466.08 g/mol
Synonyms	1,11-Bis(2-bromoacetoxy)-3,6,9-trioxaundecane; Ethanol, 2,2'-[1,2-ethanediylbis(oxy-2,1-ethanediyloxy)]bis-, 1,1'-(bromoacetyl) ester; PEG3 bis(2-bromoacetate); Tetraethylene glycol bis(2-bromoacetate); Bis(2-bromoacetoxy) tetraethylene glycol; 2,2'-(Oxybis(ethane-2,1-diyloxy))bis(ethane-2,1-diyl) bis(2-bromoacetate); Bromoacetic acid tetraethylene glycol diester
EINECS	Contact for details

Quality Control

Our 2-[2-[2-(2-Bromoacetyl)Oxyethoxy]Ethoxy]Ethyl 2-Bromoacetate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under inert conditions if prolonged exposure is anticipated to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.