Description

Drospirenone Acid Potassium Salt is a key pharmaceutical intermediate, specifically the potassium salt of the active metabolite of drospirenone. This compound is of critical importance for ensuring the purity, stability, and bioavailability of the final active pharmaceutical ingredient (API). It is primarily required by manufacturers in the pharmaceutical and fine chemical industries for the synthesis of high-purity drospirenone, a progestin used in various hormonal contraceptives and hormone replacement therapies.

Application

• Primary Pharmaceutical Intermediate: Essential for the synthesis of the active pharmaceutical ingredient (API) Drospirenone.
• Hormonal Contraceptive Production: Used in the manufacture of oral contraceptive pills containing drospirenone as the progestin component.
• Hormone Therapy Formulations: A critical building block for medications used in hormone replacement therapy (HRT).
• Fine Chemical Synthesis: Serves as a high-purity starting material or intermediate in advanced organic synthesis for related steroid derivatives.
• Research & Development: Utilized in pharmaceutical R&D labs for developing new drug formulations and conducting stability studies.
• Generic Drug Manufacturing: A vital raw material for producers of generic versions of drospirenone-based medications.

Basic Information

Item	Details
Product Name	Drospirenone Acid Potassium Salt
CAS No.	90704-90-8
Molecular Formula	C24H29KO4
Molecular Weight	420.59 g/mol
Synonyms	6β,7β;15β,16β-Dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone Potassium Salt; Potassium (6β,7β,15β,16β-Dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone); Drospirenone Potassium Salt; Drospirenone Related Compound K; ZK 30595 Potassium Salt; 17α-(2-Carboxyethyl)-6β,7β;15β,16β-bis(methylene)-3-oxo-4-androsten-17β-carboxylic Acid γ-Lactone Potassium Salt
EINECS	Contact for details

Quality Control

Our Drospirenone Acid Potassium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and related substances, to ensure it meets stringent pharmaceutical-grade specifications. We provide full traceability and support our customers with detailed Certificates of Analysis (COA) upon request, confirming compliance with relevant internal and customer-specific standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under conditions that minimize exposure to atmospheric humidity to prevent degradation or clumping.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.