Description

(T-Butyldimethylsilyloxy)Cyclopropanecarbaldehyde is a high-value, protected aldehyde building block used in advanced organic synthesis. This compound is critical for introducing the cyclopropane moiety, a key structural motif known to enhance metabolic stability and modulate biological activity in target molecules. It is primarily utilized by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates containing cyclopropane rings, particularly in antiviral, anticancer, and CNS-active compounds.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides where the cyclopropane group contributes to potency and environmental stability.
• Material Science Research: Serves as a precursor for specialty monomers or ligands in catalyst design for polymerization processes.
• Academic & Process Chemistry: Employed in methodological development and scale-up studies for complex molecule construction.
• Peptide & Protein Modification: The protected aldehyde functionality can be used for selective bioconjugation or as a handle in chemical biology probes.
• Asymmetric Synthesis: A valuable chiral starting material or intermediate for the preparation of enantiomerically pure compounds.

Basic Information

Product Name	(T-Butyldimethylsilyloxy)Cyclopropanecarbaldehyde
CAS No.	90660-09-6
Molecular Formula	C10H20O2Si
Molecular Weight	200.35 g/mol
Synonyms	Cyclopropanecarbaldehyde, 1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-; 1-((tert-Butyldimethylsilyl)oxy)cyclopropanecarbaldehyde; 1-(TBDMSO)cyclopropanecarbaldehyde; (1-(tert-Butyldimethylsilyloxy)cyclopropyl)methanal; TBDMS-protected cyclopropanecarbaldehyde; 1-[(tert-Butyldimethylsilyl)oxy]cyclopropanecarboxaldehyde
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. Certificates of Analysis (COA) are available upon request for every batch, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.